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Tarkkanen AM, Heinonen T, Jõgi R, Mentula S, van der Rest ME, Donskey CJ, Kemppainen T, Gurbanov K & Nord CE : P1A recombinant beta-lactamase prevents emergence of antimicrobial resistance in gut microflora of healthy subjects during intravenous administration of ampicillin. Antimicrob Agents Chemother. 53(6):2455-2462, 2009.
Hallier-Vanuxeem D, Prieto P, Culot M, Diallo H, Landry C, Tähti H, Cecchelli R: New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment. Toxicol In Vitro. 23(3):447-453, 2009. Nevala H, Ylikomi T & Tähti H: Evaluation of the barrier properties of ARPE-19 cell line for in vitro blood-brain barrier model. Hum Exp Toxicol 27(10):741-749, 2008. Bläuer M, Tammela TL, Ylikomi T. A novel tissue-slice culture model for non-malignant human prostate. Cell Tissue Res. 332(3):489-498, 2008. Toimela T, Tähti H & Ylikomi T: Comparison of automated pattern analysis machine vision time lapse system with traditional endpoint measurements in analyzing cell growth and cytotoxicity. ATLA 36:313-325, 2008. Bläuer M, Heinonen PK, Rovio P & Ylikomi T: Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model. Eur J Pharmacol 592(1-3):13-18, 2008. Pärssinen J, Kuukasjärvi T, Karhu R & Kallioniemi A: High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer. Br J Cancer. 96(8):1258-1264, 2007 Sarkanen JR, Nykky J, Siikanen J, Selinummi J, Ylikomi T, & Jalonen, TO: Cholesterol supports the retinoic acid-induced synaptic vesicle formation in differentiating human SH-SY5Y neuroblastoma cells. J Neurochem 102(6):1941-1952, 2007. Alarmo EL, Rauta J, Kauraniemi P, Karhu R, Kuukasjärvi T & Kallioniemi A: Bone morphogenetic protein 7 is widely overexpressed in primary breast cancer. Genes Chromosomes Cancer. 45(4):411-419, 2006. Mannerström M, Toimela T, Ylikomi T & Tähti H: The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs. Toxicol Lett 165(2):195-202, 2006. Rauta J, Alarmo EL, Kauraniemi P, Karhu R, Kuukasjärvi T & Kallioniemi A: The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours. Breast Cancer Res Treat. 95(3):257-263, 2006. Selinummi J, Sarkanen JR, Niemistö A, Linne ML, Ylikomi T, Yli-Harja O & Jalonen TO: Quantification of vesicles in differentiating human SH-SY5Y neuroblastoma cells by automated image analysis. Neurosci Lett 396(2):102-107, 2006. Bläuer M, Heinonen PK, Martikainen PM, Tomas E & Ylikomi T: A novel organotypic culture model for normal human endometrium: regulation of epithelial cell proliferation by estradiol and medroxyprogesterone acetate. Hum Reprod 20:864-871, 2005. Mannerstöm M & Tähti H: Glucose-uptake as a target of neurological drugs in glial and neuronal cell lines. Toxicol Lett, 151, 87-97, 2004. Toimela T & Tähti H: Mitochondrial viability and apoptosis induced by aluminum, mercury and methylmercury in cell lines of neural origin. Arch Toxicol, 78, 565-574, 2004. Kakko I, Toimela T & Tähti H: The toxicity of pyrethroid compounds in neural cell cultures studied with total ATP, mitochondrial enzyme activity and microscopic photographing. Environ Toxicol Pharmacol 15, 95-102, 2004. Kakko I, Toimela T &Tähti H: Oestradiol potentiates the effect of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line. Altern Lab. Anim. ATLA, 32, 383-390, 2004. Mannerström M & Tähti H: Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs. Toxicol Lett. 151(1):87-97, 2004. Toimela T, Mäenpää H, Mannerström M & Tähti H: Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum. Toxicol Appl Pharmacol. 195(1):73-82, 2004. Mäenpää H, Toimela T, Mannerström M, Saransaari P & Tähti H: Toxicity of selected cationic drugs in retinoblastomal cultures and in cocultures of retinoblastomal and retinal pigment epithelial cell lines. Neurochem Res. 29(1):305-11, 2004. Szabó A, Varga V, Toimela T, Hiitelä K, Tähti H, Oja SS, Süveges I & Salminen L: Laser treatment of cultured retinal pigment epithelial cells-evaluation of the cellular damage in vitro. J Ocul Pharmacol Ther. 20(3):246-255, 2004. |



